MCCB精神分裂症认知功能成套测验共识版（MATRICS）
 
MCCB精神分裂症认知功能成套测验共识版（MATRICS）（Measurement and Treatment Research to Improve Cognition in Schizophrenia (MATRICS) Consensus Cognitive Battery），目的是采用专家投票选择和结合临床测试而达成共识的测验，来测量被诊断为精神分裂症和相关疾病的个体的认知能力，以及帮助研究开发对改善精神分裂症患者认知有效的药物。
 
开发者：Keith H.Nuechterlein博士和Michael F.Green博士
测试年龄范围：20岁至59岁
测试时间：60-90分钟
施测管理：个人单独测试
格式：纸笔测试，软件
资质等级：C
 
功能和优点

• 一款标准化测试套装。由10项单独进行的测试组成，测量七个领域的认知表现：处理速度、注意力/警惕性、工作记忆、言语学习、视觉学习、推理和解决问题以及社会认知。
• 得到了美国国立卫生研究院（NIH）、美国国家精神卫生研究所(NIMH)、美国食品药品监督管理局（FDA）和相关领域的专家的支持。MCCB是由学术界、美国国家卫生研究院、美国食品药物监督管理局以及制药行业组成的一个独特的基础广泛的共识过程的结果。
• MCCB适用于多种用途。旨在对与精神分裂症和相关疾病相关的关键认知领域进行相对简短的评估，适合用作认知增强药物临床试验的结果测量，在研究认知修复时，测量认知变化，并作为精神分裂症和其他严重精神疾病非干预研究的认知参考点。

 
测试结构

• MCCB中的10项测试中的每一项都应单独进行。测试通常可以在1到1个半小时的时间内完成。
• MCCB管理员表格用于记录一名被测者的结果。对于两项测试，MCCB管理员表格中附有一本单独的小册子或表格。对于三项测试，被测者在MCCB受访者小册子中进行标记。对于一个测试，使用计算机程序进行响应。
• MCCB套件包括用于整个测试的25次施测管理的材料。MCCB重测包包括额外的25次施测管理所需的材料。施测材料也可以适用于其他形式。
• 包括修订后的软件和第三版手册。

 
套件中包含修订后的软件和手册

• 除了评分CD外，每个MCCB套件还包括一个用于PDF下载的串行代码。
• MCCB评分程序允许输入主要原始分数，并为七个认知领域中的每一个提供相应的T分数和百分位数以及T分数的图形轮廓。评分程序还允许您将数据输入到统计程序中进行分组分析。
• MCCB软件的最新更新（包括MCCB评分程序、MSCEIT分支4评分程序和CPT-IP程序）包括：

扩展的功能。
使用美国以外国家和地区的规范性数据的选项。

• MSCEIT Branch 4 Scoring Program的更新包括国际版本的开发，因此用户可以根据北美规范或国际规范为MSCEIT生成标准分数。还增加了新的安全功能。
• CPT-IP程序的更新允许使用20多种语言的屏幕说明，因此受访者可以在开始测试前用自己的母语查看这些说明。
• 新的MCCB手册第三版及增补，包含在MCCB套件中。

 
MCCB精神分裂症认知功能成套测验共识版套装，型号：5875-KT，包括：
1本MCCB手册、25份MCCB管理员表格、25本MCCB响应者手册、1个软件磁盘[包含CPT-IP、MSCEIT评分程序和MCCB评分程序]、1个BACS符号编码任务评分模板、1个WMS-III空间跨度板、25份HVLT-R测试小册子-表格1、1份BVMT-R回忆刺激小册子，25份执行功能模块反应小册子、25份NAB迷宫测试记录表格，所有产品都放在一个MCCB的储存盒内。

• 请仔细阅读以下本产品重要说明。

• 语言：英文
• 计分表格：纸张
• 国际惯例：相应的专业人员购买并使用
• 产品主要参数：MCCB（Measurement and Treatment Research to Improve Cognition in Schizophrenia (MATRICS) Consensus Cognitive Battery）
• 原装进口，产地美国
• 尊重并维护知识产权，请按以下列表选择购买使用量表类产品，以实现教学、科研等工作的严谨性和信效度

套装
5875-KT	MCCB精神分裂症认知功能成套测验共识版，套装	电邮询价

 
 MCCB精神分裂症认知功能成套测验共识版（MATRICS）（Measurement and Treatment Research to Improve Cognition in Schizophrenia (MATRICS) Consensus Cognitive Battery），文献索引（部分）：

• Curr Top Behav Neurosci. 2023;63:1-18. doi: 10.1007/7854_2022_395.

《The MATRICS Consensus Cognitive Battery: An Update》

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《Cross-diagnostic determinants of cognitive functioning: the muscarinic cholinergic receptor as a model system》

• Front Hum Neurosci. 2022 Nov 21;16:1094810. doi: 10.3389/fnhum.2022.1094810. eCollection 2022.

《Corrigendum: The association between metabolic disturbance and cognitive impairments in early-stage schizophrenia》

• Front Psychiatry. 2022 Dec 1;13:1075222. doi: 10.3389/fpsyt.2022.1075222. eCollection 2022.

《Cognitive functioning in a group of adolescents at risk for psychosis》

• J Affect Disord. 2022 Aug 1;310:369-376. doi: 10.1016/j.jad.2022.04.153. Epub 2022 Apr 30.

《The prevalence and characteristics of MCCB cognitive impairment in unmedicated patients with bipolar II depression and major depressive disorder》

• Schizophr Res Cogn. 2022 Mar 22;29:100249. doi: 10.1016/j.scog.2022.100249. eCollection 2022 Sep.

《Cognitive dysfunction in schizophrenia: An expert group paper on the current state of the art》

• Psychol Med. 2022 Aug 3;1-8. doi: 10.1017/S0033291722002148. Online ahead of print.

《The relationship between cognitive clusters and telomere length in bipolar-schizophrenia spectrum disorders》

• Neuroimage Clin. 2022;35:103056. doi: 10.1016/j.nicl.2022.103056. Epub 2022 May 23.

《Multimodal data fusion of cortical-subcortical morphology and functional network connectivity in psychotic spectrum disorder》

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《Corrigendum: The association between cognitive deficits and clinical characteristic in first-episode drug naïve patients with schizophrenia》

• Front Psychiatry. 2022 Oct 13;13:1024299. doi: 10.3389/fpsyt.2022.1024299. eCollection 2022.

《Alterations in innate immune defense distinguish first-episode schizophrenia patients from healthy controls》

• Psychiatry Res Neuroimaging. 2022 Aug 28;326:111536. doi: 10.1016/j.pscychresns.2022.111536. Online ahead of print.

《Abnormal fractional Amplitude of Low-Frequency Fluctuation in chronic ketamine users》

• Schizophr Res. 2022 Jan;239:47-54. doi: 10.1016/j.schres.2021.11.019. Epub 2021 Nov 26.

《Computerized or manual? Long term effects of cognitive remediation on schizophrenia》

• Ann Gen Psychiatry. 2022 Feb 10;21(1):4. doi: 10.1186/s12991-022-00381-7.

《Aberrant cortical surface and cognition function in drug-naive first-episode schizophrenia》

• BMC Psychiatry. 2022 Sep 26;22(1):628. doi: 10.1186/s12888-022-04240-3.

《Building a neurocognitive profile of suicidal risk in severe mental disorders》

• Front Hum Neurosci. 2022 Apr 22;16:853994. doi: 10.3389/fnhum.2022.853994. eCollection 2022.

《Correlation Between Resting Theta Power and Cognitive Performance in Patients With Schizophrenia》

• J Clin Med. 2022 Apr 6;11(7):2044. doi: 10.3390/jcm11072044.

《Emotional Processing Profile in Patients with First Episode Schizophrenia: The Influence of Neurocognition》

• Schizophr Res. 2022 Aug;246:103-111. doi: 10.1016/j.schres.2022.06.008. Epub 2022 Jun 23.

《Aberrant functional connectivity within the salience network is related to cognitive deficits and disorganization in psychosis》

• Obes Surg. 2022 Jul;32(7):2299-2308. doi: 10.1007/s11695-022-06076-y. Epub 2022 Apr 29.

《Correlations Between Endocrine Hormones and Cognitive Function in Patients with Obesity: a Cross-sectional Study》

• Schizophr Res Cogn. 2022 Sep 5;30:100270. doi: 10.1016/j.scog.2022.100270. eCollection 2022 Dec.

《Dispersion of cognitive performance test scores on the MATRICS Consensus Cognitive Battery: A different perspective》

• Front Psychiatry. 2022 Sep 16;13:998807. doi: 10.3389/fpsyt.2022.998807. eCollection 2022.

《Cognitive dysfunction and cortical structural abnormalities in first-episode drug-naïve schizophrenia patients with auditory verbal hallucination》

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《Association of NKAPL rs1635 With Cognitive Function in Early-Onset Schizophrenia》

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《Altered regional homogeneity and cognitive impairments in first-episode schizophrenia: A resting-state fMRI study》

• J Clin Med. 2022 May 6;11(9):2619. doi: 10.3390/jcm11092619.

《The Relationship between Cognitive Functions and Psychopathological Symptoms in First Episode Psychosis and Chronic Schizophrenia》

• Front Psychiatry. 2022 Jan 7;12:825681. doi: 10.3389/fpsyt.2021.825681. eCollection 2021.

《Negative Symptom Domains Are Associated With Verbal Learning in Adolescents With Early Onset Psychosis》

• Schizophr Res. 2021 May;231:179-188. doi: 10.1016/j.schres.2021.04.001. Epub 2021 Apr 16.

《Cortical morphometric correlational networks associated with cognitive deficits in first episode schizophrenia》

• Front Psychol. 2021 Jun 21;12:648346. doi: 10.3389/fpsyg.2021.648346. eCollection 2021.

《The Relationship Between Facial Expression and Cognitive Function in Patients With Depression》

• Lancet Psychiatry. 2021 Mar;8(3):191-201. doi: 10.1016/S2215-0366(20)30513-7.

《Efficacy and safety of the novel glycine transporter inhibitor BI 425809 once daily in patients with schizophrenia: a double-blind, randomised, placebo-controlled phase 2 study》

• Front Psychiatry. 2021 Mar 25;12:645471. doi: 10.3389/fpsyt.2021.645471. eCollection 2021.

《Cortical Thickness Changes in Chronic Ketamine Users》

• Sci Rep. 2021 Apr 7;11(1):7577. doi: 10.1038/s41598-021-87172-4.

《A bottom-up model of functional outcome in schizophrenia》

• Asian J Psychiatr. 2021 Feb;56:102559. doi: 10.1016/j.ajp.2021.102559. Epub 2021 Jan 13.

《Association between global visual scanning and cognitive function in schizophrenia》

• J Med Invest. 2020;67(1.2):75-82. doi: 10.2152/jmi.67.75.

《Predictors of life skills in people with schizophrenia》

• J Affect Disord. 2020 Mar 15;265:132-138. doi: 10.1016/j.jad.2020.01.052. Epub 2020 Jan 14.

《Psychometric properties of the MATRICS Consensus Cognitive Battery (MCCB) in Chinese patients with major depressive disorder》

• Schizophr Res. 2020 Jun;220:172-178. doi: 10.1016/j.schres.2020.03.036. Epub 2020 Mar 30.

《Effects of an extrinsic motivator on the evaluation of cognitive and daily living functions in patients with schizophrenia》

• Front Psychiatry. 2020 Jul 10;11:603. doi: 10.3389/fpsyt.2020.00603. eCollection 2020.

《White Matter Measures and Cognition in Schizophrenia》

• Psychiatry Investig. 2020 Jul;17(7):695-701. doi: 10.30773/pi.2020.0085. Epub 2020 Jul 8.

《Correlation between Performance-Based and Interview-Based Cognitive Measurements in Patients with Schizophrenia》

• Psychol Med. 2020 Jul;50(10):1623-1632. doi: 10.1017/S0033291719001582. Epub 2019 Jul 12.

《Transdiagnostic validity of the MATRICS Consensus Cognitive Battery across the autism-schizophrenia spectrum》

• Gen Psychiatr. 2019 Jul 22;32(3):e100043. doi: 10.1136/gpsych-2018-100043. eCollection 2019.

《Meta-analysis of cognitive function in Chinese first-episode schizophrenia: MATRICS Consensus Cognitive Battery (MCCB) profile of impairment》

• Schizophr Res. 2019 Jun;208:317-323. doi: 10.1016/j.schres.2019.01.034. Epub 2019 Feb 1.

《What is the optimal neuropsychological test battery for schizophrenia in China?》

• Brain Stimul. 2019 Jan-Feb;12(1):54-61. doi: 10.1016/j.brs.2018.10.002. Epub 2018 Oct 2.

《Transcranial direct-current stimulation in ultra-treatment-resistant schizophrenia》

• Pharmacol Rep. 2018 Aug;70(4):639-649. doi: 10.1016/j.pharep.2018.01.009. Epub 2018 Feb 2.

《Assessment of cognitive functions in animal models of schizophrenia.》

• J Neuropsychiatry Clin Neurosci. 2019 Fall;31(4):368-377. doi: 10.1176/appi.neuropsych.18060131. Epub 2019 May 23.

《Association of Working Memory With Distributed Executive Control Networks in Schizophrenia》

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《Cognitive impairment and its improvement after six months in adolescents with schizophrenia》